BEGIN:VCALENDAR
VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Allan P. Colburn Memorial Lecture: Adrianne Rosales\, The Univ
 ersity of Texas at Austin
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260616T094046Z
UID:tag:localist.com\,2008:EventInstance_45950647426479
DTSTART:20240510T141500Z
DTEND:20240510T151500Z
DESCRIPTION:Multiscale Control of Dynamic Hydrogels for Bioinspired Applica
 tions\n\n \n\nTransient polymer networks are found throughout biological s
 ystems\, both intracellularly and extracellularly. Hydrogels with dynamic 
 linkers have garnered intense interest as extracellular matrix (ECM) mimic
 s and injectable delivery vehicles due to their tailorable viscoelasticity
 \, stress relaxation\, and self-healing behavior. However\, to fully enabl
 e these applications\, there remains a need to understand how linking chem
 istry affects gelation and nonlinear rheological properties. In this conte
 xt\, we have developed synthetic multi-arm poly(ethylene glycol) (PEG) hyd
 rogels with three different dynamic covalent linking chemistries. This sui
 te of dynamic covalent linkages allows control over the bond exchange kine
 tics across three orders of magnitude\, which dictates hydrogel viscoelast
 icity under small amplitude oscillatory shear. Interestingly\, the hydroge
 l moduli demonstrate unique scaling behavior at low concentrations\, indic
 ating heterogeneous networks. Furthermore\, they exhibit non-monotonic flo
 w curves under steady shear\, with shear thickening behavior that depends 
 on the crosslinking bond exchange kinetics and polymer concentration. At h
 igh shear\, the dynamic hydrogels are injectable\, with faster bond exchan
 ge kinetics leading to lower injection forces. Overall\, these results pro
 vide insight to the molecular and structural characteristics that govern d
 ynamic covalent PEG gelation\, mechanics\, and flow\, while also expanding
  the types of scaffolds applicable to tissue engineering and therapeutic d
 elivery.
GEO:39.680031;-75.749885
LOCATION:Colburn Lab\, 102
SUMMARY:Allan P. Colburn Memorial Lecture: Adrianne Rosales\, The Universit
 y of Texas at Austin
URL;VALUE=URI:https://events.udel.edu/event/allan-p-colburn-memorial-lectur
 e-adrianne-rosales-the-university-of-texas-at-austin
CATEGORIES:Academics
CATEGORIES:College of Engineering
END:VEVENT
END:VCALENDAR