Image-based modeling of skeletal muscle: from lab to clinic to market

Presented by: 

Silvia Salinas Blemker

University of Virginia

• Skeletal muscles are extraordinarily adapted motors that enable us to perform many important functions, from walking to sight to speech. Thus, muscle dysfunction arising from muscle injury, atrophy, degeneration, fatty infiltration, and fibrosis present major health care problems. The goal of the Multi-Scale Muscle Mechanophysiology (“M3”) Lab’s research is to develop imaging and computational modeling techniques that allow us to quantify muscle structure and assess functional impairments for various applications. We aim to apply these methods to answering questions related to the role of complex muscle biology and mechanics in various contexts, including muscular dystrophy, muscle injury, athletic performance, and muscle regeneration.  In this presentation, I will describe these approaches and present a range of contexts that span from the lab to clinic to the market.