CBE Seminar: Chase Beisel, NC State University
The CRISPR Revolution
CRISPR has become synonymous with disruptive genome-editing technologies that are revolutionizing basic research, biotechnology, medicine, and agriculture. One critical aspect of CRISPR often overlooked in this fanfare is that it was not invented; instead, CRISPR is naturally part of adaptive immune systems in bacteria and archaea called CRISPR-Cas systems. These systems have proven remarkably diverse and stand in stark contrast to small handful of proteins currently used as technologies. In this talk, I will describe the unique properties of CRISPR-Cas systems and how these properties directly lend to genome editing and many other uses. I will also describe my group's ongoing efforts to explore the functional diversity of these systems and how they can be harnessed for applications in bacterial strain engineering and programmable-spectrum antimicrobials. Through these advances, we aim to understand the functional diversity of these versatile immune systems and further advance the reach and impact of the ensuing revolutionary technologies.
Friday, September 8, 2017 at 10:00am to 11:00am
Colburn Lab, Room 102
University of Delaware- Colburn Lab, University of Delaware, 150 Academy St, Newark, DE 19716-3196, USA