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CATEGORIES:Students,Academics,College of Engineering,Community,Lectures and
  Programs
DESCRIPTION:“Bilingual Peptide Nucleic Acids: Encoding the Languages of Nuc
 leic Acids and Proteins in a Single Self-Assembling Biopolymer”\n\nNature e
 ncodes information\, structure\, and function in two basic forms of biopoly
 mers: nucleic acids and proteins. Although Nature has evolved machinery to 
 read the nucleic acid code and translate it into amino acid code\, the exta
 nt biopolymers are restricted to encoding amino acid or nucleotide sequence
 s separately\, limiting their potential applications in medicine and biotec
 hnology. We demonstrate the design\, synthesis\, and stimuliresponsive asse
 mbly behavior of a bilingual biopolymer that integrates both amino acid and
  nucleobase sequences into a single peptide nucleic acid (PNA) scaffold to 
 enable tunable storage and retrieval of tertiary structural behavior and pr
 ogrammable molecular recognition capabilities. Incorporation of a defined s
 equence of amino acid side-chains along the PNA backbone yields amphiphiles
  having a “protein code” that directs self-assembly into micellar architect
 ures in aqueous conditions. However\, these amphiphiles also carry a “nucle
 otide code” such that subsequent introduction of a complementary RNA strand
  induces a sequence-specific disruption of assemblies through hybridization
 . Together\, these properties establish bilingual PNA as a powerful biopoly
 mer that combines two information systems to harness structural responsiven
 ess and sequence recognition.\n\n \n\n“Self-Care Is Not the Enemy of Perfor
 mance”\n\nThe highly competitive nature of academic environments might seem
  to suggest that success can only be obtained at the cost of taking good ca
 re of oneself. However\, sacrificing self-care can be extremely harmful. Th
 is seminar will discuss ways that high performance and self-care can be mut
 ually reinforcing and produce long-term success. A key goal is for each per
 son to take away a set of practical strategies and habits they can employ t
 o support their mental and physical health while also supporting their futu
 re success in research.\n\n \n\nRegistration required.\n\nSeminar LINK will
  be sent after registration is completed.
DTEND:20210514T160000Z
DTSTAMP:20260414T214915Z
DTSTART:20210514T140000Z
LOCATION:
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SUMMARY:CRiSP Seminar:  Prof. Jennifer Heemstra\, Emory University
UID:tag:localist.com\,2008:EventInstance_36343702358544
URL:https://events.udel.edu/event/crisp_seminar_prof_jennifer_heemstra_emor
 y_university
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